Publications from my lab in reverse chronological order:

Wang LL; Li J; Gu X; Wei L; Yu SP, 2017. Delayed treatment of 6-Bromoindirubin-3'-oxime stimulates neurogenesis and functional recovery after focal ischemic stroke in mice.  Int J Dev Neurosci 57:77-84

Wang ZH; Liu P; Liu X; Manfredsson FP; Sandoval IM; Yu SP; Wang JZ; Ye K, 2017. Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.  Mol Cell 67(5):812-825.e5

Song M; Yu SP; Mohamad O; Cao W; Wei ZZ; Gu X; Jiang MQ; Wei L, 2017. Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice.  Neurobiol Dis 98:9-24

Jiang MQ; Zhao YY; Cao W; Wei ZZ; Gu X; Wei L; Yu SP, 2017. Long-term survival and regeneration of neuronal and vasculature cells inside the core region after ischemic stroke in adult mice.  Brain Pathol 27(4):480-498

Wei L; Wei ZZ; Jiang MQ; Mohamad O; Yu SP, 2017. Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke.  Prog Neurobiol 157:49-78

Zhao Y; Wei ZZ; Zhang JY; Zhang Y; Won S; Sun J; Yu SP; Li J; Wei L, 2017. GSK-3β Inhibition Induced Neuroprotection, Regeneration, and Functional Recovery After Intracerebral Hemorrhagic Stroke.  Cell Transplant 26(3):395-407

Lee JH; Zhang J; Yu SP, 2017. Neuroprotective mechanisms and translational potential of therapeutic hypothermia in the treatment of ischemic stroke.  Neural Regen Res 12(3):341-350

Zhao Y; Lee JH; Chen D; Gu X; Caslin A; Li J; Yu SP; Wei L, 2017. DL-3-n-butylphthalide induced neuroprotection, regenerative repair, functional recovery and psychological benefits following traumatic brain injury in mice.  Neurochem Int.

Wang S; Gu X; Paudyal R; Wei L; Dix TA; Yu SP; Zhang X, 2017. Longitudinal MRI evaluation of neuroprotective effects of pharmacologically induced hypothermia in experimental ischemic stroke.  Magn Reson Imaging 40:24-30

Zhang Z; Obianyo O; Dall E; Du Y; Fu H; Liu X; Kang SS; Song M; Yu SP; Cabrele C; Schubert M; Li X; Wang JZ; Brandstetter H; Ye K, 2017. Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.  Nat Commun 8:14740

Samantaray S; Das A; Matzelle DC; Yu SP; Wei L; Varma A; Ray SK; Banik NL, 2016. Administration of low dose estrogen attenuates gliosis and protects neurons in acute spinal cord injury in rats.  J Neurochem 136(5):1064-73

Lee JH; Wei L; Deveau TC; Gu X; Yu SP, 2016. Expression of the NMDA receptor subunit GluN3A (NR3A) in the olfactory system and its regulatory role on olfaction in the adult mouse.  Brain Struct Funct 221(6):3259-73

Samantaray S; Das A; Matzelle DC; Yu SP; Wei L; Varma A; Ray SK; Banik NL, 2016. Administration of low dose estrogen attenuates persistent inflammation, promotes angiogenesis, and improves locomotor function following chronic spinal cord injury in rats.  J Neurochem 137(4):604-17

Wei ZZ; Lee JH; Zhang Y; Zhu YB; Deveau TC; Gu X; Winter MM; Li J; Wei L; Yu SP, 2016. Intracranial Transplantation of Hypoxia-Preconditioned iPSC-Derived Neural Progenitor Cells Alleviates Neuropsychiatric Defects After Traumatic Brain Injury in Juvenile Rats.  Cell Transplant 25(5):797-809

Lee JH; Wei ZZ; Cao W; Won S; Gu X; Winter M; Dix TA; Wei L; Yu SP, 2016. Regulation of therapeutic hypothermia on inflammatory cytokines, microglia polarization, migration and functional recovery after ischemic stroke in mice.  Neurobiol Dis 96:248-260

Lee JH; Espinera AR; Chen D; Choi KE; Caslin AY; Won S; Pecoraro V; Xu GY; Wei L; Yu SP, 2016. Neonatal inflammatory pain and systemic inflammatory responses as possible environmental factors in the development of autism spectrum disorder of juvenile rats.  J Neuroinflammation 13(1):109

Lee JH; Wei L; Gu X; Won S; Wei ZZ; Dix TA; Yu SP, 2016. Improved Therapeutic Benefits by Combining Physical Cooling With Pharmacological Hypothermia After Severe Stroke in Rats.  Stroke 47(7):1907-13

Yan J; Hu S; Zou K; Xu M; Wang Q; Miao X; Yu SP; Xu GY, 2016. Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation.  Sci Rep 6:38188

Lee JH; Wei ZZ; Chen D; Gu X; Wei L; Yu SP, 2015. A neuroprotective role of the NMDA receptor subunit GluN3A (NR3A) in ischemic stroke of the adult mouse.  Am J Physiol Cell Physiol 308(7):C570-7

Francis KR; Wei L; Yu SP, 2015. SRC tyrosine kinases regulate neuronal differentiation of mouse embryonic stem cells via modulation of voltage-gated sodium channel activity.  Neurochem Res 40(4):674-87

Wei ZZ; Gu X; Ferdinand A; Lee JH; Ji X; Ji XM; Yu SP; Wei L, 2015. Intranasal delivery of bone marrow mesenchymal stem cells improved neurovascular regeneration and rescued neuropsychiatric deficits after neonatal stroke in rats.  Cell Transplant 24(3):391-402

Gu X; Wei ZZ; Espinera A; Lee JH; Ji X; Wei L; Dix TA; Yu SP, 2015. Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats.  Exp Neurol 267:135-142

Lee JH; Zhang J; Wei L; Yu SP, 2015. Neurodevelopmental implications of the general anesthesia in neonate and infants.  Exp Neurol 272:50-60

Ban K; Wile B; Cho KW; Kim S; Song MK; Kim SY; Singer J; Syed A; Yu SP; Wagner M; Bao G; Yoon YS, 2015. Non-genetic Purification of Ventricular Cardiomyocytes from Differentiating Embryonic Stem Cells through Molecular Beacons Targeting IRX-4.  Stem Cell Reports 5(6):1239-49

Woodbury A; Yu SP; Chen D; Gu X; Lee JH; Zhang J; Espinera A; García PS; Wei L, 2015. Honokiol for the Treatment of Neonatal Pain and Prevention of Consequent Neurobehavioral Disorders.  J Nat Prod 78(11):2531-6

Chen D; Lee J; Gu X; Wei L; Yu SP, 2015. Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice.  ASN Neuro 7.

Chen D; Yu SP; Wei L, 2014. Ion channels in regulation of neuronal regenerative activities.  Transl Stroke Res 5(1):156-62

Liu X; Ye R; Yan T; Yu SP; Wei L; Xu G; Fan X; Jiang Y; Stetler RA; Liu G; Chen J, 2014. Cell based therapies for ischemic stroke: from basic science to bedside.  Prog Neurobiol 115:92-115

Wang LL; Chen D; Lee J; Gu X; Alaaeddine G; Li J; Wei L; Yu SP, 2014. Mobilization of endogenous bone marrow derived endothelial progenitor cells and therapeutic potential of parathyroid hormone after ischemic stroke in mice.  PLoS One 9(2):e87284

Zhang Z; Liu X; Schroeder JP; Chan CB; Song M; Yu SP; Weinshenker D; Ye K, 2014. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease.  Neuropsychopharmacology 39(3):638-50

Song M; Yu SP, 2014. Ionic regulation of cell volume changes and cell death after ischemic stroke.  Transl Stroke Res 5(1):17-27

Song M; Chen D; Yu SP, 2014. The TRPC channel blocker SKF 96365 inhibits glioblastoma cell growth by enhancing reverse mode of the Na(+) /Ca(2+) exchanger and increasing intracellular Ca(2+).  Br J Pharmacol 171(14):3432-47

Liu XB; Wang JA; Ji XY; Yu SP; Wei L, 2014. Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats.  Stem Cell Res Ther 5(5):111

Wei ZZ; Yu SP; Lee JH; Chen D; Taylor TM; Deveau TC; Yu AC; Wei L, 2014. Regulatory role of the JNK-STAT1/3 signaling in neuronal differentiation of cultured mouse embryonic stem cells.  Cell Mol Neurobiol 34(6):881-93

Chen D; Song M; Mohamad O; Yu SP, 2014. Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells.  BMC Cancer 14:716

Zhang Z; Song M; Liu X; Kang SS; Kwon IS; Duong DM; Seyfried NT; Hu WT; Liu Z; Wang JZ; Cheng L; Sun YE; Yu SP; Levey AI; Ye K, 2014. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.  Nat Med 20(11):1254-62

Lee JH; Wei L; Gu X; Wei Z; Dix TA; Yu SP, 2014. Therapeutic effects of pharmacologically induced hypothermia against traumatic brain injury in mice.  J Neurotrauma 31(16):1417-30

Song M; Mohamad O; Chen D; Yu SP, 2013. Coordinated development of voltage-gated Na+ and K+ currents regulates functional maturation of forebrain neurons derived from human induced pluripotent stem cells.  Stem Cells Dev 22(10):1551-63

Li WL; Yu SP; Chen D; Yu SS; Jiang YJ; Genetta T; Wei L, 2013. The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice.  Neuroscience 244:16-30

Song M; Mohamad O; Gu X; Wei L; Yu SP, 2013. Restoration of intracortical and thalamocortical circuits after transplantation of bone marrow mesenchymal stem cells into the ischemic brain of mice.  Cell Transplant 22(11):2001-15

Ho SL; Huang LF; Lu CA; He SL; Wang CC; Yu SP; Chen J; Yu SM, 2013. Sugar starvation- and GA-inducible calcium-dependent protein kinase 1 feedback regulates GA biosynthesis and activates a 14-3-3 protein to confer drought tolerance in rice seedlings.  Plant Mol Biol 81(4-5):347-61

Wei N; Yu SP; Gu X; Taylor TM; Song D; Liu XF; Wei L, 2013. Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice.  Cell Transplant 22(6):977-91

Mohamad O; Song M; Wei L; Yu SP, 2013. Regulatory roles of the NMDA receptor GluN3A subunit in locomotion, pain perception and cognitive functions in adult mice.  J Physiol 591(1):149-68

Zou J; Ainscough JF; Yang W; Sedo A; Yu SP; Mei ZZ; Sivaprasadarao A; Beech DJ; Jiang LH, 2013. A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.  Am J Physiol Cell Physiol 305(1):C61-9

Moon SH; Ban K; Kim C; Kim SS; Byun J; Song MK; Park IH; Yu SP; Yoon YS, 2013. Development of a novel two-dimensional directed differentiation system for generation of cardiomyocytes from human pluripotent stem cells.  Int J Cardiol 168(1):41-52

Gu H; Yu SP; Gutekunst CA; Gross RE; Wei L, 2013. Inhibition of the Rho signaling pathway improves neurite outgrowth and neuronal differentiation of mouse neural stem cells.  Int J Physiol Pathophysiol Pharmacol 5(1):11-20

Ban K; Wile B; Kim S; Park HJ; Byun J; Cho KW; Saafir T; Song MK; Yu SP; Wagner M; Bao G; Yoon YS, 2013. Purification of cardiomyocytes from differentiating pluripotent stem cells using molecular beacons that target cardiomyocyte-specific mRNA.  Circulation 128(17):1897-909

Woodbury A; Yu SP; Wei L; García P, 2013. Neuro-modulating effects of honokiol: a review.  Front Neurol 4:130

Mohamad O; Drury-Stewart D; Song M; Faulkner B; Chen D; Yu SP; Wei L, 2013. Vector-free and transgene-free human iPS cells differentiate into functional neurons and enhance functional recovery after ischemic stroke in mice.  PLoS One 8(5):e64160

Mohamad O; Yu SP; Chen D; Ogle M; Song M; Wei L, 2013. Efficient neuronal differentiation of mouse ES and iPS cells using a rotary cell culture protocol.  Differentiation 86(4-5):149-58

Yu SP; Wei Z; Wei L, 2013. Preconditioning strategy in stem cell transplantation therapy.  Transl Stroke Res 4(1):76-88

Xu Q; Huang S; Song M; Wang CE; Yan S; Liu X; Gaertig MA; Yu SP; Li H; Li S; Li XJ, 2013. Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.  J Cell Biol 202(7):1123-38

Wei S; Sun J; Li J; Wang L; Hall CL; Dix TA; Mohamad O; Wei L; Yu SP, 2013. Acute and delayed protective effects of pharmacologically induced hypothermia in an intracerebral hemorrhage stroke model of mice.  Neuroscience 252:489-500

Wei N; Yu SP; Gu XH; Chen DD; Whalin MK; Xu GL; Liu XF; Wei L, 2013. The involvement of autophagy pathway in exaggerated ischemic brain damage in diabetic mice.  CNS Neurosci Ther 19(10):753-63

Zeng X; Yu SP; Taylor T; Ogle M; Wei L, 2012. Protective effect of apelin on cultured rat bone marrow mesenchymal stem cells against apoptosis.  Stem Cell Res 8(3):357-67

Li J; Li JP; Zhang X; Lu Z; Yu SP; Wei L, 2012. Expression of heparanase in vascular cells and astrocytes of the mouse brain after focal cerebral ischemia.  Brain Res 1433:137-44

Hong Y; Chan CB; Kwon IS; Li X; Song M; Lee HP; Liu X; Sompol P; Jin P; Lee HG; Yu SP; Ye K, 2012. SRPK2 phosphorylates tau and mediates the cognitive defects in Alzheimer's disease.  J Neurosci 32(48):17262-72

Wei L; Fraser JL; Lu ZY; Hu X; Yu SP, 2012. Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats.  Neurobiol Dis 46(3):635-45

Choi KE; Hall CL; Sun JM; Wei L; Mohamad O; Dix TA; Yu SP, 2012. A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice.  FASEB J 26(7):2799-810

Li J; Zhao SZ; Wang PP; Yu SP; Zheng Z; Xu X, 2012. Calcium mediates high glucose-induced HIF-1α and VEGF expression in cultured rat retinal Müller cells through CaMKII-CREB pathway.  Acta Pharmacol Sin 33(8):1030-6

Drury-Stewart D; Song M; Mohamad O; Yu SP; Wei L, 2011. Small molecule promoted feeder free and adherent differentiation of functional neurons from human embryonic and induced pluripotent stem cells.  J Stem Cells 6(1):1-7

Zhou X; Song M; Chen D; Wei L; Yu SP, 2011. Potential role of KCNQ/M-channels in regulating neuronal differentiation in mouse hippocampal and embryonic stem cell-derived neuronal cultures.  Exp Neurol 229(2):471-83

Song EL; Hou YP; Yu SP; Chen SG; Huang JT; Luo T; Kong LP; Xu J; Wang HQ, 2011. EFEMP1 expression promotes angiogenesis and accelerates the growth of cervical cancer in vivo.  Gynecol Oncol 121(1):174-80

Zhou X; Wei J; Song M; Francis K; Yu SP, 2011. Novel role of KCNQ2/3 channels in regulating neuronal cell viability.  Cell Death Differ 18(3):493-505

Hu X; Wei L; Taylor TM; Wei J; Zhou X; Wang JA; Yu SP, 2011. Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation.  Am J Physiol Cell Physiol 301(2):C362-72

Mohamad O; Chen D; Zhang L; Hofmann C; Wei L; Yu SP, 2011. Erythropoietin reduces neuronal cell death and hyperalgesia induced by peripheral inflammatory pain in neonatal rats.  Mol Pain 7:51

Samantaray S; Sribnick EA; Das A; Thakore NP; Matzelle D; Yu SP; Ray SK; Wei L; Banik NL, 2010. Neuroprotective efficacy of estrogen in experimental spinal cord injury in rats.  Ann N Y Acad Sci 1199:90-4

Zeng XJ; Yu SP; Zhang L; Wei L, 2010. Neuroprotective effect of the endogenous neural peptide apelin in cultured mouse cortical neurons.  Exp Cell Res 316(11):1773-83

Li Y; Yu SP; Mohamad O; Genetta T; Wei L, 2010. Sublethal transient global ischemia stimulates migration of neuroblasts and neurogenesis in mice.  Transl Stroke Res 1(3):184-96

Li J; Li Y; Ogle M; Zhou X; Song M; Yu SP; Wei L, 2010. DL-3-n-butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway.  Brain Res 1359:216-26

Jiang J; Wang J; Li C; Yu SP; Wei L, 2009. Dual roles of tumor necrosis factor-alpha receptor-1 in a mouse model of hindlimb ischemia.  Vasc Med 14(1):37-46

Ogle ME; Yu SP; Wei L, 2009. Primed for lethal battle: a step forward to enhance the efficacy and efficiency of stem cell transplantation therapy.  J Thorac Cardiovasc Surg 138(3):527

Hu X; Yu SP; Fraser JL; Lu Z; Ogle ME; Wang JA; Wei L, 2008. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis.  J Thorac Cardiovasc Surg 135(4):799-808

Cui L; Jiang J; Wei L; Zhou X; Fraser JL; Snider BJ; Yu SP, 2008. Transplantation of embryonic stem cells improves nerve repair and functional recovery after severe sciatic nerve axotomy in rats.  Stem Cells 26(5):1356-65

Theus MH; Wei L; Cui L; Francis K; Hu X; Keogh C; Yu SP, 2008. In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain.  Exp Neurol 210(2):656-70

Wei JF; Wei L; Zhou X; Lu ZY; Francis K; Hu XY; Liu Y; Xiong WC; Zhang X; Banik NL; Zheng SS; Yu SP, 2008. Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility.  J Cell Physiol 217(2):544-57

Li Y; Ogle ME; Wallace GC 4th; Lu ZY; Yu SP; Wei L, 2008. Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice.  Acta Neurochir Suppl 105:105-12

Li J; Lu Z; Li WL; Yu SP; Wei L, 2008. Cell death and proliferation in NF-kappaB p50 knockout mouse after cerebral ischemia.  Brain Res 1230:281-9

Li WL; Yu SP; Ogle ME; Ding XS; Wei L, 2008. Enhanced neurogenesis and cell migration following focal ischemia and peripheral stimulation in mice.  Dev Neurobiol 68(13):1474-86

Liu XB; Wang JA; Yu SP; Keogh CL; Wei L, 2008. Therapeutic strategy of erythropoietin in neurological disorders.  CNS Neurol Disord Drug Targets 7(3):227-34

Whitaker VR; Cui L; Miller S; Yu SP; Wei L, 2007. Whisker stimulation enhances angiogenesis in the barrel cortex following focal ischemia in mice.  J Cereb Blood Flow Metab 27(1):57-68

Li Y; Lu Z; Keogh CL; Yu SP; Wei L, 2007. Erythropoietin-induced neurovascular protection, angiogenesis, and cerebral blood flow restoration after focal ischemia in mice.  J Cereb Blood Flow Metab 27(5):1043-54

Takata T; Hood AY; Yu SP, 2007. Voltage-dependent and Src-mediated regulation of NMDA receptor single channel outward currents in cortical neurons.  Cell Biochem Biophys 47(2):257-70

Keogh CL; Yu SP; Wei L, 2007. The effect of recombinant human erythropoietin on neurovasculature repair after focal ischemic stroke in neonatal rats.  J Pharmacol Exp Ther 322(2):521-8

Theus MH; Wei L; Francis K; Yu SP, 2006. Critical roles of Src family tyrosine kinases in excitatory neuronal differentiation of cultured embryonic stem cells.  Exp Cell Res 312(16):3096-107

Wei L; Han BH; Li Y; Keogh CL; Holtzman DM; Yu SP, 2006. Cell death mechanism and protective effect of erythropoietin after focal ischemia in the whisker-barrel cortex of neonatal rats.  J Pharmacol Exp Ther 317(1):109-16

Lu ZY; Yu SP; Wei JF; Wei L, 2006. Age-related neural degeneration in nuclear-factor kappaB p50 knockout mice.  Neuroscience 139(3):965-78

Abdalah R; Wei L; Francis K; Yu SP, 2006. Valinomycin-induced apoptosis in Chinese hamster ovary cells.  Neurosci Lett 405(1-2):68-73

Yang A; Wang XQ; Sun CS; Wei L; Yu SP, 2005. Inhibitory effects of clofilium on membrane currents associated with Ca channels, NMDA receptor channels and Na+, K+-ATPase in cortical neurons.  Pharmacology 73(3):162-8

Wei L; Cui L; Snider BJ; Rivkin M; Yu SS; Lee CS; Adams LD; Gottlieb DI; Johnson EM Jr; Yu SP; Choi DW, 2005. Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia.  Neurobiol Dis 19(1-2):183-93

Wei L; Keogh CL; Whitaker VR; Theus MH; Yu SP, 2005. Angiogenesis and stem cell transplantation as potential treatments of cerebral ischemic stroke.  Pathophysiology 12(1):47-62

Wang XQ; Yu SP, 2005. Novel regulation of Na, K-ATPase by Src tyrosine kinases in cortical neurons.  J Neurochem 93(6):1515-23

Sheline CT; Takata T; Ying H; Canzoniero LM; Yang A; Yu SP; Choi DW, 2004. Potassium attenuates zinc-induced death of cultured cortical astrocytes.  Glia 46(1):18-27

Wei L; Xiao AY; Jin C; Yang A; Lu ZY; Yu SP, 2004. Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons.  Pflugers Arch 448(3):325-34

Wei L; Ying DJ; Cui L; Langsdorf J; Yu SP, 2004. Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats.  Brain Res 1022(1-2):54-61

Wei L; Yu SP; Gottron F; Snider BJ; Zipfel GJ; Choi DW, 2003. Potassium channel blockers attenuate hypoxia- and ischemia-induced neuronal death in vitro and in vivo.  Stroke 34(5):1281-6

Wang XQ; Xiao AY; Yang A; LaRose L; Wei L; Yu SP, 2003. Block of Na+,K+-ATPase and induction of hybrid death by 4-aminopyridine in cultured cortical neurons.  J Pharmacol Exp Ther 305(2):502-6

Wang XQ; Xiao AY; Sheline C; Hyrc K; Yang A; Goldberg MP; Choi DW; Yu SP, 2003. Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress.  J Cell Sci 116(Pt 10):2099-110

Ichinose T; Yu S; Wang XQ; Yu SP, 2003. Ca2+-independent, but voltage- and activity-dependent regulation of the NMDA receptor outward K+ current in mouse cortical neurons.  J Physiol 551(Pt 2):403-17

Yu SP, 2003. Na(+), K(+)-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death.  Biochem Pharmacol 66(8):1601-9

Yu SP, 2003. Regulation and critical role of potassium homeostasis in apoptosis.  Prog Neurobiol 70(4):363-86

Xia S; Lampe PA; Deshmukh M; Yang A; Brown BS; Rothman SM; Johnson EM Jr; Yu SP, 2002. Multiple channel interactions explain the protection of sympathetic neurons from apoptosis induced by nerve growth factor deprivation.  J Neurosci 22(1):114-22

Xiao AY; Wei L; Xia S; Rothman S; Yu SP, 2002. Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons.  J Neurosci 22(4):1350-62

Xiao AY; Wang XQ; Yang A; Yu SP, 2002. Slight impairment of Na+,K+-ATPase synergistically aggravates ceramide- and beta-amyloid-induced apoptosis in cortical neurons.  Brain Res 955(1-2):253-9

Heidinger V; Manzerra P; Wang XQ; Strasser U; Yu SP; Choi DW; Behrens MM, 2002. Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.  J Neurosci 22(13):5452-61

Yu SP; Canzoniero LM; Choi DW, 2001. Ion homeostasis and apoptosis.  Curr Opin Cell Biol 13(4):405-11

Manzerra P; Behrens MM; Canzoniero LM; Wang XQ; Heidinger V; Ichinose T; Yu SP; Choi DW, 2001. Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity.  Proc Natl Acad Sci U S A 98(20):11055-61

Xiao AY; Homma M; Wang XQ; Wang X; Yu SP, 2001. Role of K(+) efflux in apoptosis induced by AMPA and kainate in mouse cortical neurons.  Neuroscience 108(1):61-7

Kerchner GA; Canzoniero LM; Yu SP; Ling C; Choi DW, 2000. Zn2+ current is mediated by voltage-gated Ca2+ channels and enhanced by extracellular acidity in mouse cortical neurones.  J Physiol 528 Pt 1:39-52

Yu SP; Choi DW, 2000. Ions, cell volume, and apoptosis.  Proc Natl Acad Sci U S A 97(17):9360-2

Wang X; Xiao AY; Ichinose T; Yu SP, 2000. Effects of tetraethylammonium analogs on apoptosis and membrane currents in cultured cortical neurons.  J Pharmacol Exp Ther 295(2):524-30

Snider BJ; Choi J; Turetsky DM; Canzoniero LM; Sensi SL; Sheline CT; Wang X; Yu SP; Choi DW, 2000. Nitric oxide reduces Ca(2+) and Zn(2+) influx through voltage-gated Ca(2+) channels and reduces Zn(2+) neurotoxicity.  Neuroscience 100(3):651-61

Yu SP; Yeh C; Strasser U; Tian M; Choi DW, 1999. NMDA receptor-mediated K+ efflux and neuronal apoptosis.  Science 284(5412):336-9

Behrens MM; Strasser U; Heidinger V; Lobner D; Yu SP; McDonald JW; Won M; Choi DW, 1999. Selective activation of group II mGluRs with LY354740 does not prevent neuronal excitotoxicity.  Neuropharmacology 38(10):1621-30

Yu SP; Yeh CH; Gottron F; Wang X; Grabb MC; Choi DW, 1999. Role of the outward delayed rectifier K+ current in ceramide-induced caspase activation and apoptosis in cultured cortical neurons.  J Neurochem 73(3):933-41

Yu SP; Kerchner GA, 1998. Endogenous voltage-gated potassium channels in human embryonic kidney (HEK293) cells.  J Neurosci Res 52(5):612-7

Yu SP; Farhangrazi ZS; Ying HS; Yeh CH; Choi DW, 1998. Enhancement of outward potassium current may participate in beta-amyloid peptide-induced cortical neuronal death.  Neurobiol Dis 5(2):81-8

Sensi SL; Canzoniero LM; Yu SP; Ying HS; Koh JY; Kerchner GA; Choi DW, 1997. Measurement of intracellular free zinc in living cortical neurons: routes of entry.  J Neurosci 17(24):9554-64

Yu SP; Choi DW, 1997. Na(+)-Ca2+ exchange currents in cortical neurons: concomitant forward and reverse operation and effect of glutamate.  Eur J Neurosci 9(6):1273-81

Yu SP; Sensi SL; Canzoniero LM; Buisson A; Choi DW, 1997. Membrane-delimited modulation of NMDA currents by metabotropic glutamate receptor subtypes 1/5 in cultured mouse cortical neurons.  J Physiol 499 ( Pt 3):721-32

Yu SP; Yeh CH; Sensi SL; Gwag BJ; Canzoniero LM; Farhangrazi ZS; Ying HS; Tian M; Dugan LL; Choi DW, 1997. Mediation of neuronal apoptosis by enhancement of outward potassium current.  Science 278(5335):114-7

Buisson A; Yu SP; Choi DW, 1996. DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons.  Eur J Neurosci 8(1):138-43

Dugan LL; Gabrielsen JK; Yu SP; Lin TS; Choi DW, 1996. Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons.  Neurobiol Dis 3(2):129-35

Lynch JJ 3rd; Yu SP; Canzoniero LM; Sensi SL; Choi DW, 1995. Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists.  J Pharmacol Exp Ther 273(1):554-60

Gubitosi-Klug RA; Yu SP; Choi DW; Gross RW, 1995. Concomitant acceleration of the activation and inactivation kinetics of the human delayed rectifier K+ channel (Kv1.1) by Ca(2+)-independent phospholipase A2.  J Biol Chem 270(7):2885-8

Yu SP, 1995. Roles of arachidonic acid, lipoxygenases and phosphatases in calcium-dependent modulation of M-current in bullfrog sympathetic neurons.  J Physiol 487 ( Pt 3):797-811

Csernansky CA; Canzoniero LM; Sensi SL; Yu SP; Choi DW, 1994. Delayed application of aurintricarboxylic acid reduces glutamate-induced cortical neuronal injury.  J Neurosci Res 38(1):101-8

Yu SP; O'Malley DM; Adams PR, 1994. Regulation of M current by intracellular calcium in bullfrog sympathetic ganglion neurons.  J Neurosci 14(6):3487-99

Yu SP; Van der Kloot W, 1991. Increasing quantal size at the mouse neuromuscular junction and the role of choline.  J Physiol 433:677-704

Yu SP; Van der Kloot W, 1990. Non-quantal acetylcholine release at mouse neuromuscular junction: effects of elevated quantal release and aconitine.  Neurosci Lett 117(1-2):111-6

Lupa MT; Yu SP, 1986. A comparison of miniature end-plate potentials at normal, denervated, and long-term botulinum toxin type A poisoned frog neuromuscular junctions.  Pflugers Arch 407(5):476-81

Tabti N; Lupa MT; Yu SP; Thesleff S, 1986. Pharmacological characterization of the calcium-insensitive, intermittent acetylcholine release at the rat neuromuscular junction.  Acta Physiol Scand 128(3):429-36

Lupa MT; Tabti N; Thesleff S; Vyskocil F; Yu SP, 1986. The nature and origin of calcium-insensitive miniature end-plate potentials at rodent neuromuscular junctions.  J Physiol 381:607-18

Yu SP; Liu CG, 1985. [Antagonism of non-depolarization muscle relaxants and aminoglycoside antibiotics to the block of neuromuscular junction of the rat diaphragm caused by soman].  Zhongguo Yao Li Xue Bao 6(1):11-6

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